The Arf subfamily is involved in vesicle transport and membrane trafficking. Additionally, guanine dissociation inhibitors GDIs can bind to small GTPases and regulate their location in the membrane or cytoplasm. To learn more about our GDPR policies click here. If you want more info regarding data storage, please contact gdpr jove. Your access has now expired. Provide feedback to your librarian. If you have any questions, please do not hesitate to reach out to our customer success team.
Login processing Chapter 4: Protein Function. Chapter 2: Biochemistry of the Cell. Chapter 3: Protein Structure. Chapter 6: DNA Replication. Chapter Gene Expression. Chapter Mendelian Genetics. Chapter Genomes and Evolution. Chapter Cell Signaling Pathways. Chapter Analyzing Gene Expression and Function. Chapter Cell Proliferation. Chapter Cell Division. Chapter Meiosis. Chapter Cancer. Full Table of Contents. This is a sample clip. Sign in or start your free trial.
Previous Video Next Video. Next Video 4. Embed Share. Guanosine triphosphate, GTP, a close relative of ATP, is a small molecule important for the regulation of protein function. Mishra, A. Biopolymers, 8 , — Toma-Fukai, S. Molecules Basel, Switzerland , 24 18 , Please enter your institutional email to check if you have access to this content.
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These are small monomeric proteins homologous to Ras. They are also called small GTPases. Small GTPases have a molecular weight of about 21 kilo-Dalton and generally serve as molecular switches for a variety of cellular signaling events. According to their primary amino acid sequences and biochemical properties, the Ras superfamily is further divided into five subfamilies: Ras , Rho , Rab , Arf and Ran.
These GTPases play an important role in initiation, elongation and termination of protein biosynthesis. See dynamin as a prototype for large GTPases. Categories: Signal transduction EC 3. Read what you need to know about our industry portal bionity. My watch list my. My watch list My saved searches My saved topics My newsletter Register free of charge.
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