Waltham, MA: Elsevier; Skolnik AB, Monas J. Philadelphia, PA: Elsevier; chap Reviewed by: Jacob L. Editorial team. Chlorpromazine overdose. Poisonous Ingredient Chlorpromazine can be poisonous in large amounts. Where Found Chlorpromazine is found in chlorpromazine hydrochloride. Other medicines may also contain chlorpromazine.
Symptoms Below are symptoms of a chlorpromazine overdose in different parts of the body. Home Care Seek medical help right away. Before Calling Emergency Have this information ready: Person's age, weight, and condition The name of the medicine and strength, if known When it was swallowed The amount swallowed If the medicine was prescribed for the person. Poison Control Your local poison center can be reached directly by calling the national toll-free Poison Help hotline from anywhere in the United States.
What to Expect at the Emergency Room Take the container with you to the hospital, if possible. The person may receive: Breathing support, including oxygen and a tube through the mouth into the lungs and breathing machine ventilator Blood and urine tests Chest x-ray CT scan computerized axial tomography or advanced brain imaging ECG electrocardiogram, or heart tracing Intravenous fluids through a vein Laxative Medicine to reverse the effects of the drug and treat symptoms.
Outlook Prognosis Chlorpromazine is fairly safe. The situation in juvenile facilities is similar. An AP story from this year says that 52 percent of juvenile inmates have some form of mental illness. In Florida, as reported by the Palm Beach Post , juvenile authorities have come under harsh criticism for the overuse of strong antipsychotic drugs, and youth prison doctors have been accused of taking large payouts from drug companies to prescribe their products.
Time reported last year that pharmaceutical companies had paid out the largest settlement in U. Maybe society can finally begin to reverse the trend of criminalized mental illness that has taken root in the last few decades.
Of course Charges incorrigibility and truancy was filed on me. In Columbus, Ohio the old juvenile detention center, was my home eight months a year, and ninety percent of that, in my underwear in a cold dark solitary confinement cell, no blankets, concrete bunks, getting high doses of Thorazine.
S, more of the same, then D. Single mother, no father. I can tell you the months of hell in that juvenile solitary confinement broke something inside me. They also held adult mental retarted prisoners in this same isolation pod. While out for the restroom, I stole a cigarette and lighter from staff desk.
When I smoked it I was quickly discovered. That same staff member and I had problems before. Late that evening while I was drooling all over myself from my nightly Thorazine dose, he unlocked my door, and then unlocked the door of a 20 year old mentally retarted rapist, and told him my door was unlocked, he was going on break for long while.
I fought like a wild animal with that monster for what seemed like an enternity. I had just turned eleven. Chlorpromazine can affect your sleep in a few different ways — you may feel more tired and sleep more than normal, you may find it difficult to get to sleep, or you may experience nightmares.
Things should settle after the first few days. If not, you should go back to your doctor and talk through your options. When you first start to take this medication, combining alcohol with chlorpromazine will make you feel very sleepy, so you should avoid it altogether. Once your body has got more used to the chlorpromazine, this effect should be reduced.
This could lead you to increase the dose of the street drug to make up for it, which could be very dangerous. Cigarette smoke affects the amount of chlorpromazine in your body. So, if you start or stop smoking while you are taking chlorpromazine, you may have to change your dose. If you already smoke when you begin taking this medication, you will probably need a higher dose than somebody who does not smoke.
You should tell your doctor if you smoke and how much, so that he or she can prescribe the correct dose for you.
It is the smoke, rather than nicotine, that has this effect so it should not be a problem if you only vape. Tell your doctor or pharmacist if you are taking any other kind of medication as they may need to change your dose of chlorpromazine or prescribe you a different medication.
Other medications include tablets or liquids that you buy over the counter to treat common illnesses such as colds and flu, or topical medications that are applied to the skin. Chlorpromazine may make you feel very tired and woozy when you start taking it, and it may affect your eyesight, so you should not ride a bike or drive a car until you become used to this medication. Arrange alternative methods of transport for a few days or weeks until you know how you will be affected.
You should also be very careful when doing anything else that requires concentration, such as operating machinery or exercising. Chlorpromazine has been used in humans during pregnancy for a long time with no signs of increased risk to you or your unborn baby. Babies do better when their mums are mentally well, so if chlorpromazine has beneficial effects on your mental health, it may be best to continue taking it throughout pregnancy. Your doctor can help you weigh up the pros and cons.
Pregnant woman are advised to take folic acid — this is safe to do while also taking chlorpromazine. You may also be checked for increased risk of blood clots during pregnancy and may be prescribed a course of blood-thinning injections.
This is standard practice and nothing to worry about. Women taking more than mg a day of chlorpromazine may have a longer labour than might normally be expected. Chlorpromazine can cause side effects in newborn babies including withdrawal symptoms. Your baby may also have difficulty sleeping and breathing.
Talk to your midwife or doctor to discuss feeding options before your baby is born, so that you can be prepared. After you have taken chlorpromazine for a few weeks, you should begin to feel the benefits of the medication which may include improvements in your relationships and, consequently, your sex life. You should tell your doctor if you are pregnant or trying for a baby before taking chlorpromazine.
Chlorpromazine can affect your fertility. This is because it increases the amount of the hormone prolactin in the body. Prolactin is the hormone released by breastfeeding, which may have some contraceptive effect may make it harder to get pregnant. Make sure you use a reliable method of contraception while you are taking chlorpromazine if you do not wish to become pregnant.
It may make you feel tired and woozy, and affect your eyesight when you first start taking it, so you may wish to stop playing sports for the first few days, until you know more about how it affects you. Talk to your doctor before starting to take chlorpromazine if you are about to sit any exams or tests, as the medication can initially make you feel very tired and woozy, and it may affect your eyesight.
You might decide together to delay starting it until you have done them, or your doctor might suggest some alternative medications. You need to talk to your doctor or pharmacist before starting treatment with chlorpromazine if any of the following apply to you:. Young people usually take chlorpromazine for many months or years.
Your doctor should talk to you about how long you might expect to stay on this medication. Ideally, you should stay on an antipsychotic medication for four to six weeks before deciding whether to continue taking it in the long term.
This gives the medication a chance to build up in your system and to begin delivering its full effects. You will get the best effect from chlorpromazine if you take it regularly at the dose prescribed by your doctor. Make sure that you know your dose.
If it's not written on the label, check with your pharmacist or doctor. Some people start with a low dose of chlorpromazine in liquid form before moving on to tablets as their dose increases. If you do have to take your medication at school or college, ask your doctor to help you talk to a teacher or school nurse about how best to do this some people prefer to keep a separate supply of medicine at school or college, for instance - your pharmacist can help with that.
Tablets and liquid can be taken before or after food. Swallow tablets whole with a drink of water — if chewed, they taste horrible! You must visit a doctor or nurse for this and should stay lying down for 30 minutes after receiving the injection. If you forget to take this medication for a few days, your old symptoms might start coming back.
If this happens, talk to your doctor without delay. Once you start taking an antipsychotic medication, the brain adjusts to having a new level of dopamine around. If you stop taking the antipsychotic all at once, the balance starts to change again, meaning you could get your old symptoms back.
If you have taken more chlorpromazine than the dosage recommended by the doctor who prescribed it to you, you must get medical help immediately - even if you do not feel any different. If you experience any of the following symptoms, you should stop taking chlorpromazine and go to the hospital straight away:.
While taking chlorpromazine, you should stop taking your medication and see your doctor without delay if:. While taking chlorpromazine, you should not stop taking your medication but should see your doctor as soon as possible if:. While taking this medication, your doctor should carry out regular blood tests to check your liver, blood sugar and hormone levels. They may also want to do a heart test using a machine called an electrocardiogram ECG if you are at risk of heart disease.
These tests should be done regularly at the beginning of your treatment, at least once every couple of weeks, and once a year after that. Your doctor should also do blood tests to check your liver, blood sugar, and your levels of some hormones like prolactin. Your medicine box contains a leaflet which describes all known side effects for your medication, both rare and common. If you do get a side effect, please think about reporting it via the ' Yellow Card scheme '.
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